Clinical Research Trials in Primary Care

Mayford House Surgery actively supports clinical research trials in primary care. We believe that this is a great opportunity for our patients who may be eligible for studies to help shape the future of medicine. Taking part in research studies demonstrates Mayford House Surgery’s commitment to quality improvement.

There are several types of studies that we may be involved in. For some studies we may send out letters to invite patients to participate depending on if they meet certain criteria. For others we rely on patients identifying themselves from publicity around the surgery.

2024/25 Research Update

This year we have developed our research team and are working more collaboratively with Mowbray House Surgery. This enables us to be part of more interventional and commercial studies (these are run by pharmaceutical or drug companies) which we feel is important to be able to offer our patients with the aim of improving individuals’ health but also health care for the future. We are very proud to share the news that we have also recruited our first patient to our first commercial study.

Recently completed studies:

ALABAMA: looked at penicillin allergy status and its effect on antibiotic prescribing, patient outcomes, and antimicrobial resistance. We had a great response rate and those patients who were randomised for testing have had their records updated to reflect true allergy status or not.

CANAssess: tested the effectiveness of a Needs Assessment Tool for Cancer in Yorkshire. We were one of the top recruiters for this study which was a great achievement.

DISCOVER ME: this was a national commercial trial looking at diseases and the genetics behind these.

Current studies:

COAT: a trial looking at the best used of oral antibiotics in patients with leg cellulitis.

DURATION UTI: this is a randomised control (this means patients are allocated at random to different treatments) trial looking at the impact of different length antibiotic courses on resistance and the effectiveness of treatment of Urinary Tract Infections (UTI) in adult women.

iiD3: Infectious Intestinal Disease (study 3) – this is for patients 18-years and over who have had either diarrhoea or vomiting and do not already know the reason why they have it.  We would ask that you do NOT attend the surgery if you have diarrhoea or vomiting.  Our doctors and nurses will be able to help you via a telephone consultation.

OPTIMISE2: this aims to establish whether deprescribing common drugs that lower blood pressure is safe or effective in patients over the age of 75 in the longer term (a year or more).

THARROS: a clinical study looking at whether treatments for Chronic Obstructive Pulmonary Disease (COPD) may help prevent COPD flare-ups and serious heart attacks.